Polymicrobial interactions: Influenza and Pneumonia

Polymicrobial interactions: Influenza and Pneumonia

In the newly published paper by Shrestha et al., we use a mechanistic transmission model within a likelihood framework to infer the nature, strength and duration of the impact of influenza infection on subsequent risk of pneumonia.  We find evidence for a short-lived increase of ~100-fold in susceptibility to pneumonia following influenza infection.  Our collaborators on this project include Cecile Viboud (Fogarty International Center, NIH), Betsy Foxman (Epidemiology, UMich) and Wilbert van Panhuis (Pitt).